Description

(3α,5α,12β,19α,20R)-6,7-Didehydro-2α,20-Cycloaspidospermidine-3-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block and a key intermediate for the research and development of novel pharmaceutical agents. It is primarily needed by research institutions and pharmaceutical companies focused on developing new therapeutic compounds, particularly in the areas of oncology and neurological disorders.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of complex bioactive molecules and potential drug candidates.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed in advanced organic synthesis to introduce complex stereochemistry due to its multiple defined chiral centers.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories analyzing related alkaloids.
• Biochemical Research: Used in studies investigating the biological activity and mechanism of action of aspidosperma-type alkaloids.

Basic Information

Item	Details
Product Name	(3α,5α,12β,19α,20R)-6,7-Didehydro-2α,20-Cycloaspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	6822-38-4
Molecular Formula	C₂₁H₂₄N₂O₂
Molecular Weight	336.43 g/mol
Synonyms	6,7-Didehydro-2α,20-cycloaspidospermidine-3-carboxylic acid methyl ester; Methyl (3α,5α,12β,19α,20R)-6,7-didehydro-2α,20-cycloaspidospermidine-3-carboxylate; Aspidospermidine derivative; 2α,20-Cycloaspidospermidine-3-carboxylic acid methyl ester; 6822-38-4; Cycloaspidospermidine methyl ester
EINECS	Contact for details

Quality Control

Our (3α,5α,12β,19α,20R)-6,7-Didehydro-2α,20-Cycloaspidospermidine-3-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.