Description

Phenolphthalein Glucuronic Acid Sodium Salt is a specialized biochemical reagent primarily used as a chromogenic substrate for enzymatic assays. This compound is critical for research and diagnostic applications where precise detection and quantification of β-glucuronidase activity are required. It is an essential tool for professionals in pharmaceutical research, clinical diagnostics, and biochemical analysis seeking reliable and sensitive assay components.

Application

• Enzymatic Substrate for β-Glucuronidase: Used as a key chromogenic substrate in biochemical assays to detect and quantify β-glucuronidase enzyme activity, which is a marker in various diagnostic and research contexts.
• Clinical Diagnostics: Employed in the development of diagnostic kits for detecting bacterial contamination (e.g., E. coli) in water, food, and clinical samples, where β-glucuronidase serves as an indicator.
• Pharmaceutical Research: Utilized in drug metabolism and pharmacokinetic (DMPK) studies to investigate glucuronidation pathways, a major phase II detoxification reaction.
• Microbiology and Cell Biology: Applied in research to study gene expression and reporter gene assays where the β-glucuronidase (GUS) gene is used as a marker.
• Quality Control in Manufacturing: Serves as a reference standard or assay component in the quality control of enzymes and related biochemical products.

Basic Information

Product Name	Phenolphthalein Glucuronic Acid Sodium Salt
CAS No.	6820-54-8
Molecular Formula	C27H29NaO11
Molecular Weight	552.51 g/mol
Synonyms	Phenolphthalein Glucuronide Sodium Salt; Phenolphthalein Mono-β-D-Glucuronide Sodium Salt; Phenolphthalein-β-D-Glucuronic Acid Sodium Salt; 5-[3-(4-Hydroxy-3-oxo-1(3H)-isobenzofuranylidene)-2-oxopropyl]-1-thio-β-D-glucopyranosiduronic Acid Sodium Salt; PPGNa; PPG Sodium Salt; GUS Substrate Sodium Salt; β-Glucuronidase Substrate
EINECS	Contact for details

Quality Control

Our Phenolphthalein Glucuronic Acid Sodium Salt is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity research and diagnostic standards. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO; slightly soluble in methanol
pH (1% Solution)	6.0 - 8.0
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.