Description

(25R)-5β-Spirostane-1β,3β,25-Triol CAS NO 6808-26-0 is a high-purity, multi-hydroxylated spirostane derivative, a key intermediate in the synthesis of complex steroidal compounds. Its precise stereochemistry and functional group arrangement make it a valuable scaffold for pharmaceutical research and development. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development of novel therapeutic agents and as a reference standard.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroid-based drugs and bioactive molecules.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of steroidal products.
• Biochemical Research: Serves as a precursor or ligand in studies of enzyme inhibition, receptor binding, and metabolic pathways.
• Natural Product Synthesis: A key starting material for the semi-synthesis of complex natural products derived from plant sterols.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for high-value steroidal active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(25R)-5β-Spirostane-1β,3β,25-Triol
CAS No.	6808-26-0
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	(25R)-1β,3β,25-Trihydroxy-5β-spirostan; 1β,3β,25-Trihydroxyspirostan-5β-ol; (25R)-Spirostane-1β,3β,25-triol; 5β-Spirostane-1β,3β,25-triol, (25R)-; 1β,3β,25-Trihydroxy-5β-spirostane; Tigogenin-1β,3β,25-triol derivative; (25R)-1β,3β,25-Trihydroxyspirostan-5-one precursor
EINECS	Contact for details

Quality Control

Our (25R)-5β-Spirostane-1β,3β,25-Triol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.