Description

Oxazepam Glucuronide is a major, pharmacologically inactive metabolite of the anxiolytic drug oxazepam, formed via glucuronidation. This reference standard is critical for analytical and research applications, providing a definitive benchmark for identification and quantification. It is primarily required by pharmaceutical R&D laboratories, forensic toxicology units, and clinical research organizations for method development, validation, and quality control in bioanalytical studies.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the calibration of analytical instruments and validation of testing methods in drug metabolism and pharmacokinetics (DMPK) studies.
• Forensic Toxicology Analysis: Used as a key analytical standard for the precise identification and quantification of oxazepam metabolites in biological samples (e.g., blood, urine) for legal and workplace testing.
• Clinical Research & Biomarker Studies: Essential for investigating the metabolic pathways, clearance rates, and pharmacokinetic profiles of oxazepam in human subjects.
• Bioanalytical Method Development: A crucial component in developing and optimizing high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS/MS) assays.
• Quality Control in Manufacturing: Employed in the quality assurance processes of pharmaceutical manufacturers to monitor and control the purity of active pharmaceutical ingredients (APIs) and related substances.
• Academic & Institutional Research: Used in universities and research institutes for studies on drug metabolism, enzyme kinetics (UGT), and the development of new analytical techniques.

Basic Information

Product Name	Oxazepam Glucuronide
CAS No.	6801-81-6
Molecular Formula	C23H23ClN2O8
Molecular Weight	490.89 g/mol
Synonyms	7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one glucuronide; Oxazepam β-D-Glucuronide; Oxazepam Glucuronide Conjugate; Oxazepam O-Glucuronide; Oxazepam Glucuronide Metabolite; 3-Hydroxyoxazepam Glucuronide; Oxazepam D-Glucuronide; Lorazepam glucuronide related compound B (structural isomer)
EINECS	Contact for details

Quality Control

Our Oxazepam Glucuronide is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for reference materials. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.