Description

2,3-Didehydro-7-Methoxycrinan-1α-Ol is a specialized crinane alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial intermediate for the development of novel therapeutic agents, particularly those targeting neurological pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex natural product analogs and new chemical entities. The high-purity material is essential for ensuring reproducible results in both discovery and process development stages.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel crinane alkaloid derivatives with potential pharmacological activity.
• Neurological Research: Used in the study and development of compounds targeting acetylcholinesterase and other neurological receptors.
• Natural Product Synthesis: Serves as a sophisticated precursor for the total or semi-synthesis of complex Amaryllidaceae alkaloids.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize lead compounds for improved efficacy and selectivity.
• Reference Standard: Used as an analytical standard in quality control laboratories for the identification and quantification of related alkaloids.
• Biochemical Research: Applied in enzymatic and receptor-binding assays to investigate biological mechanisms.

Basic Information

Product Name	2,3-Didehydro-7-Methoxycrinan-1α-Ol
CAS No.	6793-24-4
Molecular Formula	C17H19NO3
Molecular Weight	285.34 g/mol
Synonyms	7-Methoxycrinan-1α-ol, 2,3-didehydro-; 1α-Hydroxy-2,3-didehydro-7-methoxycrinan; 2,3-Dehydro-7-methoxycrinan-1α-ol; Crinan-1α-ol, 2,3-didehydro-7-methoxy-; Galanthamine derivative intermediate; Lycorine-type alkaloid intermediate; Amaryllidaceae alkaloid synthon
EINECS	Contact for details

Quality Control

Our 2,3-Didehydro-7-Methoxycrinan-1α-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. We provide comprehensive analytical data including HPLC purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis. Certificates of Analysis (COA) documenting all critical quality attributes are available for every batch and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to prevent degradation. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.