Description

1-Stearoyl-2-Oleoyl-Sn-Glycero-3-Phosphocholine (SOPC) is a high-purity, synthetic phospholipid with a defined fatty acid composition, serving as a critical building block for advanced biomimetic systems. This compound is essential for creating stable, well-characterized lipid bilayers that accurately model biological membranes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications ranging from drug delivery to membrane biophysics.

Application

• Liposome & Nanoparticle Formulation: A key component for constructing unilamellar vesicles (LUVs, SUVs) and solid lipid nanoparticles (SLNs) for targeted drug and gene delivery systems.
• Membrane Biophysics Research: Used to create defined model membranes for studying protein-lipid interactions, membrane permeability, and fusion mechanisms.
• Biomimetic Coatings & Sensors: Employed in the development of biosensors, diagnostic assays, and biocompatible surface coatings that mimic natural cell surfaces.
• Cell Culture & Organoid Development: Acts as a supplement to create more physiologically relevant environments for advanced cell culture and 3D tissue modeling.
• Reference Standard: Serves as a high-purity analytical standard for quality control in lipidomics research and pharmaceutical development.
• Cosmetic Actives Carrier: Utilized in premium cosmetic formulations to enhance the stability and skin delivery of active ingredients.

Basic Information

Product Name	1-Stearoyl-2-Oleoyl-sn-Glycero-3-Phosphocholine
CAS No.	6753-56-6
Molecular Formula	C44H86NO8P
Molecular Weight	788.13 g/mol
Synonyms	SOPC; 18:0-18:1 PC; 1-Octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; POPC (common misnomer, correctly refers to 16:0-18:1 PC); Phosphatidylcholine (18:0/18:1(9Z)); L-α-Phosphatidylcholine, β-γ-distearoyl-oleoyl; (2R)-2,3-Bis(octadecanoyloxy)propyl (9Z-octadec-9-enoyloxy)ethyl phosphate
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-2-Oleoyl-sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity, purity, and fatty acid composition. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7 guidelines, and REACH for global supply.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Under these conditions, the product is typically stable for at least 24 months. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Phosphorus)	96.0% - 102.0% of theoretical
Fatty Acid Composition (GC)	Stearoyl (C18:0): 45-55%; Oleoyl (C18:1): 45-55%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH limits
Peroxide Value	≤ 3.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.