Description

Linoleoyl Coenzyme A is a critical biochemical intermediate, specifically a thioester derivative of linoleic acid and coenzyme A. This compound is essential for research into lipid metabolism, serving as a key substrate for enzymes involved in fatty acid elongation, desaturation, and β-oxidation pathways. It is primarily utilized by biochemists, pharmaceutical researchers, and academic institutions focused on metabolic disorders, biofuel development, and the synthesis of complex lipids.

Application

• Biochemical Research: Fundamental substrate for studying fatty acid metabolism, enzyme kinetics (e.g., desaturases, elongases), and lipid biosynthesis pathways.
• Pharmaceutical Development: Used in in vitro assays to investigate drug targets for metabolic diseases such as diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).
• Nutritional Science: A tool for researching the metabolism of essential polyunsaturated fatty acids (PUFAs) and their impact on cellular health.
• Enzyme Characterization: Serves as a standard or substrate for purifying and characterizing acyl-CoA synthetases, thioesterases, and transferases.
• Biofuel & Synthetic Biology: Investigated as a precursor in engineered metabolic pathways for the production of advanced biofuels and oleochemicals.
• Cell Signaling Studies: Used to explore the role of lipid-derived signaling molecules and their precursors in cellular communication.

Basic Information

Product Name	Linoleoyl Coenzyme A
CAS No.	6709-57-5
Molecular Formula	C39H68N7O17P3S
Molecular Weight	1040.0 g/mol (approx.)
Synonyms	Linoleoyl-CoA; (9Z,12Z)-Octadecadienoyl-CoA; Coenzyme A, S-(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl ester; Linoleoyl-coenzyme A; 9,12-Linoleoyl-CoA; cis,cis-9,12-Octadecadienoyl-CoA; C18:2-CoA; Linoleic acid CoA ester
EINECS	Contact for details

Quality Control

Our Linoleoyl Coenzyme A is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability parameters. We adhere to ISO 9001 quality management principles, and our analytical methods are validated to meet the exacting standards required for biochemical research reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized. For long-term stability, it is recommended to store desiccated. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 3.0%
Biological Activity	Functional in standard enzyme assays
Solubility	Soluble in water or appropriate aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.