Description

β-Belladonnine is a tropane alkaloid of significant interest in pharmaceutical research and development. This compound serves as a crucial intermediate and reference standard for the synthesis and analysis of bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies focused on neurological and pharmacological studies, where precise chemical standards are paramount for ensuring experimental integrity and regulatory compliance.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, GC-MS) for quality control of drug substances and herbal extracts.
• Biochemical Research: Serves as a key intermediate or tool compound in studies investigating the mechanism of action of tropane alkaloids and their derivatives.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a critical building block in the synthetic pathways for developing novel therapeutic agents.
• Academic Research: Employed in university and institutional labs for pharmacological profiling and structural-activity relationship (SAR) studies.
• Analytical Method Development: Essential for developing and validating chromatographic and spectroscopic assays in compliance with ICH guidelines.

Basic Information

Product Name	β-Belladonnine
CAS No.	6696-63-5
Molecular Formula	C17H21NO2
Molecular Weight	271.35 g/mol
Synonyms	Belladonnine; 3α-Tigloyloxytropane; Tropan-3α-yl (2Z)-2-methylbut-2-enoate; DL-Belladonnine; (±)-Belladonnine; 3-Tigloyloxytropane; NSC 209989
EINECS	Contact for details

Quality Control

Every batch of β-Belladonnine is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, GC, and spectroscopic methods. Our quality protocols are designed to meet the stringent requirements of pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.