Description

11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Butyrate is a high-purity steroid derivative, specifically a butyrate ester of hydrocortisone. This compound is a critical pharmaceutical intermediate valued for its role in the synthesis of more complex corticosteroid APIs. It is essential for manufacturers in the pharmaceutical and fine chemical industries requiring reliable, high-quality building blocks for advanced drug development and production.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent topical and systemic corticosteroid drugs.
• Steroid API Synthesis: Used in the research and development of novel anti-inflammatory and immunosuppressive agents.
• Biochemical Research: Serves as a reference standard and a tool compound in metabolic and hormonal pathway studies.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized steroid-based products.

Basic Information

Item	Detail
Product Name	11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Butyrate
CAS No.	6677-99-2
Molecular Formula	C25H36O6
Molecular Weight	432.55 g/mol
Synonyms	Hydrocortisone 21-Butyrate; Cortisol 21-Butyrate; 11β,17,21-Trihydroxypregn-4-ene-3,20-dione 21-butyrate; Prednisolone derivative; (11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione 21-butanoate; NSC 113927
EINECS	Contact for details

Quality Control

Our 11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Butyrate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.