Description

Uridine Diphosphate 2-Deoxyglucose is a crucial nucleotide sugar derivative, serving as a key biochemical tool and metabolic intermediate. Its primary value lies in its role as a specific inhibitor of glycosylation processes and as a substrate analog in enzymatic studies of carbohydrate metabolism. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly for investigating glucose metabolism, cancer cell energetics, and developing novel therapeutic strategies.

Application

• Biochemical Research: Used as a substrate analog to study enzymes like glycogen synthase, glycosyltransferases, and other carbohydrate-metabolizing enzymes.
• Metabolic Pathway Inhibition: Acts as a specific inhibitor of protein N-glycosylation and other glycosylation pathways in cell culture and in vitro systems.
• Cancer Research: Employed in studies of the Warburg effect and altered glucose metabolism in tumor cells, aiding in the development of diagnostic and therapeutic agents.
• Pharmaceutical Development: Serves as a critical reference standard and intermediate in the synthesis of novel nucleoside-based drugs and metabolic probes.
• Enzymology Assays: Utilized in high-throughput screening (HTS) assays to identify modulators of glycosyltransferase activity for drug discovery.
• Diagnostic Reagent Manufacturing: A key component in formulating diagnostic kits for metabolic disorders and enzymatic deficiencies.

Basic Information

Product Name	Uridine Diphosphate 2-Deoxyglucose
CAS No.	6659-40-1
Molecular Formula	C15H22N2O16P2
Molecular Weight	548.28 g/mol
Synonyms	UDP-2-Deoxyglucose; UDP-2-Deoxy-D-glucose; Uridine 5'-(trihydrogen diphosphate) P'→5'-ester with 2-deoxy-D-glucose; 2-Deoxyglucose-UDP; UDP-2DG; Uridine diphospho-2-deoxyglucose; Uridine 5'-diphospho-2-deoxy-D-glucose
EINECS	Contact for details

Quality Control

Our Uridine Diphosphate 2-Deoxyglucose is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details
Biological Activity	Contact for details
Endotoxin	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.