Description

Sancycline Hydrochloride CAS NO 6625-20-3 is a chemically modified tetracycline derivative, primarily valued as a key intermediate in pharmaceutical synthesis. Its significance lies in its role as a precursor for the development of novel semi-synthetic tetracycline antibiotics, which are crucial in addressing antibiotic resistance. This high-purity compound is essential for research institutions and manufacturers in the pharmaceutical and biotechnology sectors focused on antimicrobial drug discovery and development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of next-generation tetracycline-class antibiotics, such as tigecycline analogs.
• Antimicrobial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and mechanisms of action against resistant bacterial strains.
• Reference Standard: Serves as a high-purity analytical reference standard in quality control (QC) and research and development (R&D) laboratories for method development and validation.
• Chemical Synthesis: Employed in organic synthesis for the preparation of novel chemical entities with potential therapeutic applications beyond antibiotics.

Basic Information

Product Name	Sancycline Hydrochloride
CAS No.	6625-20-3
Molecular Formula	C22H24N2O8 • HCl
Molecular Weight	480.90 g/mol
Synonyms	6-Deoxy-6-demethyltetracycline Hydrochloride; 6-Deoxytetracycline Hydrochloride; Santycin Hydrochloride; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Hydrochloride; 6-Desmethyl-6-deoxytetracycline HCl; Antibiotic U-24729A
EINECS	Contact for details

Quality Control

Our Sancycline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and tests for residual solvents and heavy metals, to ensure it meets stringent standards for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.