Description

(-)-Nicotine Mono Tartrate CAS NO 6550-19-2 is the specific levorotatory enantiomer of nicotine combined with tartaric acid, forming a stable, crystalline salt. This high-purity form is critical for applications requiring precise stereochemistry and consistent biological activity. It is an essential intermediate and reference standard for the pharmaceutical, agrochemical, and life science research industries.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the calibration and validation of analytical methods (e.g., HPLC, GC) in drug development and quality control.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key chiral building block in the synthesis of nicotine-based therapeutics, including smoking cessation aids and neurological research compounds.
• Biochemical Research: Employed in receptor binding studies, enzymatic assays, and pharmacological research targeting nicotinic acetylcholine receptors (nAChRs).
• Agrochemical Formulations: Used in the research and development of next-generation, enantiomerically pure insecticides and pesticides.
• Diagnostic Reagent Manufacturing: A critical component in the production of diagnostic kits and assays for clinical and forensic toxicology.
• E-liquid & Nicotine Replacement Therapy (NRT) Research: Provides a high-purity, standardized nicotine source for advanced research into vaping formulations and therapeutic patches/gums.

Basic Information

Product Name	(-)-Nicotine Mono Tartrate
CAS No.	6550-19-2
Molecular Formula	C14H18N2O6 or (C10H14N2)·C4H6O6
Molecular Weight	310.30 g/mol
Synonyms	(-)-Nicotine Bitartrate; (S)-Nicotine Hydrogen Tartrate; L-Nicotine Tartrate; Nicotine Acid Tartrate; Nicotine (1:1) Tartrate Salt; Nicotine Tartrate Monohydrate (common form); (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine tartrate; 1-Methyl-2-(3-pyridyl)pyrrolidine (+)-tartrate
EINECS	229-474-5

Quality Control

Our (-)-Nicotine Mono Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, residual solvents, and specific rotation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Specific Rotation [α]20/D	-78° to -82° (c=2 in H2O)
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥ 99.0% (S)-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.