Description

1,2-Linoleoylphosphatidylcholine is a specific, high-purity phospholipid where linoleic acid is esterified at both the sn-1 and sn-2 positions of the glycerol backbone. This compound matters as a critical functional ingredient and research standard due to its defined molecular structure and role as a primary source of linoleic acid in biological membranes. It is essential for manufacturers and researchers in the pharmaceutical, nutraceutical, and advanced lipidomics sectors who require precise, well-characterized phospholipids for formulation development, drug delivery systems, and metabolic studies.

Application

• Liposome & Drug Delivery Systems: A key structural and functional component for creating stable liposomal formulations to enhance drug solubility, targeting, and controlled release.
• Pharmaceutical Excipients: Used in solid dosage forms and injectables as a solubilizer, emulsifier, and bioavailability enhancer for poorly soluble active pharmaceutical ingredients (APIs).
• Nutraceutical & Dietary Supplements: Incorporated into supplements targeting liver health, cognitive function, and as a source of essential fatty acids in phospholipid complexes.
• Biochemical Research & Diagnostics: Serves as a standard or substrate in lipidomics research, enzyme assays (e.g., phospholipase studies), and membrane biophysics experiments.
• Cosmetic Formulations: Acts as a high-performance emollient and skin barrier repair agent in premium skincare products for its moisturizing and restorative properties.
• Cell Culture Media: Used as a lipid supplement in specialized serum-free media to support the growth and maintenance of certain cell lines.

Basic Information

Product Name	1,2-Linoleoylphosphatidylcholine
CAS No.	6542-05-8
Molecular Formula	C44H82NO8P
Molecular Weight	784.09 g/mol
Synonyms	1,2-Dilinoleoyl-sn-glycero-3-phosphocholine; PC(18:2/18:2); Dilinoleoylphosphatidylcholine; Phosphatidylcholine, dilinoleoyl; Linoelaidylphosphatidylcholine; 3-sn-Phosphatidylcholine 1,2-di-(9Z,12Z-octadecadienoyl); DLPC; 1,2-Di-Linoleoyl-Phosphatidylcholine
EINECS	229-458-0

Quality Control

Our 1,2-Linoleoylphosphatidylcholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, to ensure compliance with stringent specifications suitable for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed container to reach room temperature before opening to prevent condensation and minimize exposure to air.

Specification

Item	Specification
Appearance	Yellowish waxy solid or viscous liquid
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (Total Phospholipids)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 5.0 meq/kg
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.