Description

(8S,9R)-3-Dehydro-11-Hydrocinchonan-9-Ol CAS NO 6536-33-0 is a high-purity, stereochemically defined alkaloid derivative belonging to the cinchona family. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, particularly for the development of pharmaceuticals and asymmetric catalysts. It is essential for research and production in fine chemical, pharmaceutical, and academic laboratories where precise stereochemistry and high purity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antimalarial and antiarrhythmic drugs.
• Asymmetric Catalyst Synthesis: Used in the preparation of chiral ligands and organocatalysts for enantioselective chemical reactions.
• Fine Chemical Research: Serves as a valuable reference standard and starting material in medicinal chemistry and process development.
• Alkaloid Chemistry Studies: Employed in academic and industrial research to study the structure-activity relationships of cinchona alkaloids.

Basic Information

Product Name	(8S,9R)-3-Dehydro-11-Hydrocinchonan-9-Ol
CAS No.	6536-33-0
Molecular Formula	C19H22N2O2
Molecular Weight	310.39 g/mol
Synonyms	11-Hydrocinchonan-9-ol, 3-dehydro-; 3-Dehydro-11-hydroxycinchonan-9-ol; (8S,9R)-3-Dehydro-11-hydroxycinchonan-9-ol; Dihydrocinchonine derivative; Cinchona alkaloid derivative; 9-Hydroxy-3-dehydro-11-hydrocinchonan; (8S,9R)-9-Hydroxy-10,11-dihydrocinchonan-3-one
EINECS	Contact for details

Quality Control

Our (8S,9R)-3-Dehydro-11-Hydrocinchonan-9-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.