Description

Nazasetron is a selective serotonin 5-HT3 receptor antagonist, a class of compounds with significant therapeutic value. Its primary commercial importance lies in its role as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) in the development of antiemetic medications. This product is essential for research institutions, pharmaceutical development companies, and fine chemical suppliers engaged in the synthesis of novel therapeutics targeting nausea and vomiting, particularly in oncology and post-operative care. We supply high-purity Nazasetron CAS NO 123039-99-6 to support global innovation in the life sciences sector.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of advanced 5-HT3 receptor antagonist drugs.
• Active Pharmaceutical Ingredient (API) Development: Serves as the core active compound for formulating antiemetic medications.
• Oncology Supportive Care: Used in research and production of drugs to prevent chemotherapy-induced nausea and vomiting (CINV).
• Post-operative Nausea and Vomiting (PONV) Prevention: Key component in therapeutics designed for surgical recovery.
• Biochemical Research: Tool compound for studying serotonin receptor pathways and neuropharmacology.
• Reference Standard: Serves as a high-purity standard for analytical testing and quality control in pharmaceutical manufacturing.

Basic Information

Item	Detail
Product Name	Nazasetron
CAS No.	123039-99-6
Molecular Formula	C17H20N4O2
Molecular Weight	312.37 g/mol
Synonyms	Nazasetron; 123039-99-6; Y-25130; 1H-Indazole-3-carboxamide, 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-; 1-Methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxamide; Y 25130; Y25130; UNII-8VZQ2R8FQY
EINECS	Contact for details

Quality Control

Our Nazasetron is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. Our quality commitment aligns with cGMP (current Good Manufacturing Practice) principles where applicable, ensuring traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.