Description

Coenzyme A-Glutathione Mixed Disulfide is a critical biochemical conjugate formed between coenzyme A and glutathione. This compound matters as a key intermediate in cellular redox metabolism and thiol-disulfide exchange processes, influencing energy production and antioxidant defense mechanisms. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical sectors for biochemical research, enzyme studies, and the development of metabolic pathway modulators.

Application

• Biochemical Research: Used as a substrate or standard in studies of mitochondrial function, fatty acid metabolism, and redox signaling pathways.
• Enzyme Activity Assays: Serves as a cofactor or modulator in assays for enzymes like glutathione peroxidase and various acyl-CoA synthetases.
• Pharmaceutical Development: Investigated as a potential intermediate or active component in drugs targeting metabolic disorders, oxidative stress, and aging.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits for measuring cellular energy status or oxidative stress markers.
• Nutraceutical Formulation: Explored for use in advanced supplement blends aimed at supporting cellular energy production and detoxification.
• Cell Culture & Media Supplementation: Used in specialized cell culture media to support specific metabolic functions in research applications.

Basic Information

Product Name	Coenzyme A-Glutathione Mixed Disulfide
CAS No.	6477-52-7
Molecular Formula	C52H84N15O26P3S2
Molecular Weight	1524.37 g/mol
Synonyms	CoA-GSH Mixed Disulfide; Glutathione-CoA Mixed Disulfide; Coenzyme A and Glutathione Disulfide; S-(Glutathionyl)-Coenzyme A; CoA-SSG; CAS 6477-52-7; CoA-GSSG
EINECS	Contact for details

Quality Control

Our Coenzyme A-Glutathione Mixed Disulfide is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.