Description

2-Butynoyl-Coenzyme A is a specialized biochemical reagent and a key intermediate in the study of fatty acid metabolism and enzyme kinetics. This high-purity compound is essential for researchers and manufacturers requiring precise tools for metabolic pathway analysis and biochemical assay development. It is primarily utilized in pharmaceutical R&D, academic biochemistry, and the production of diagnostic kits where accurate modeling of metabolic processes is critical.

Application

• Biochemical Research: Serves as a critical substrate for studying acyl-CoA dehydrogenases and other enzymes involved in fatty acid β-oxidation pathways.
• Pharmaceutical Development: Used as a reference standard and intermediate in the research of metabolic disorders and the development of targeted therapeutics.
• Diagnostic Assay Manufacturing: Employed in the formulation of enzymatic test kits for clinical diagnostics and metabolic profiling.
• Enzyme Kinetics & Inhibition Studies: Acts as a specific substrate to investigate enzyme mechanism, activity, and for screening potential inhibitors.
• Academic & Institutional Laboratories: Provides a reliable tool for graduate-level research and advanced studies in biochemistry and molecular biology.
• Biotechnology: Used in metabolic engineering research to understand and manipulate CoA-dependent biochemical networks.

Basic Information

Product Name	2-Butynoyl-Coenzyme A
CAS No.	6244-99-1
Molecular Formula	C25H40N7O17P3S
Molecular Weight	867.60 g/mol
Synonyms	2-Butynoyl-CoA; But-2-ynoyl-Coenzyme A; 2-Butynoylcoenzyme A; Coenzyme A, S-(2-butynoate); Butynoyl-CoA; 3-Oxobut-1-ynyl-CoA; Acetylene-analog of Acetoacetyl-CoA; 2-Butynoyl-Coenzyme A Lithium Salt (common salt form)
EINECS	Contact for details

Quality Control

Every batch of 2-Butynoyl-Coenzyme A is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identification, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.