Description

Dl-Dihydroorotic Acid CAS NO 6202-10-4 is a key intermediate in the biosynthesis of pyrimidine nucleotides, serving as a vital building block in cellular metabolism. This compound is essential for research and development in life sciences, particularly in studying nucleotide synthesis pathways and enzyme functions. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on metabolic research and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleotide analogs and active pharmaceutical ingredients (APIs) targeting metabolic disorders.
• Biochemical Research: Used as a substrate or standard in enzymatic assays to study dihydroorotate dehydrogenase (DHODH) and other enzymes in the pyrimidine synthesis pathway.
• Cell Culture & Media Supplement: Employed in specialized cell culture media formulations to support the growth of certain cell lines requiring pyrimidine precursors.
• Nutritional Science: Investigated for its role in nucleotide metabolism and potential applications in specialized nutritional products.
• Reference Standard: Serves as a high-purity analytical reference standard for quality control and method development in pharmaceutical and bioanalytical laboratories.

Basic Information

Product Name	Dl-Dihydroorotic Acid
CAS No.	6202-10-4
Molecular Formula	C5H6N2O4
Molecular Weight	158.11 g/mol
Synonyms	DL-4,5-Dihydroorotic Acid; (RS)-4,5-Dihydroorotic Acid; 2,6-Dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic Acid; 6-Carboxy-2,4-dihydroxypyrimidine; Dihydroorotate; NSC 66975; Orotic acid, dihydro-; Racemic Dihydroorotic Acid
EINECS	228-269-7

Quality Control

Our Dl-Dihydroorotic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be kept under dry conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.