Description

Bz-Tyr-Pna CAS NO 6154-45-6 is a protected tyrosine derivative, specifically N-Benzoyl-L-tyrosine p-nitroanilide, widely used as a key synthetic intermediate and chromogenic substrate. This compound is valued for its role in the synthesis of more complex peptides and as a specialized reagent in biochemical research. It is primarily needed by pharmaceutical R&D laboratories, peptide synthesis service providers, and manufacturers of diagnostic enzyme substrates.

Application

• Peptide Synthesis Intermediate: Serves as a crucial building block in the solid-phase and solution-phase synthesis of complex peptides and peptide mimetics.
• Enzyme Substrate: Acts as a chromogenic p-nitroanilide (pNA) substrate for studying the activity and kinetics of proteolytic enzymes like chymotrypsin and other serine proteases.
• Biochemical Research: Used in academic and industrial research for developing and optimizing enzymatic assays and screening for enzyme inhibitors.
• Pharmaceutical Development: Employed in the research and development of new therapeutic agents, particularly those targeting protease-related pathways.
• Reference Standard: Utilized as a high-purity analytical standard for quality control in related chemical and biological production.

Basic Information

Product Name	Bz-Tyr-Pna
CAS No.	6154-45-6
Molecular Formula	C22H19N3O5
Molecular Weight	405.41 g/mol
Synonyms	N-Benzoyl-L-tyrosine p-nitroanilide; Bz-Tyr-pNA; Nα-Benzoyl-L-tyrosine 4-nitroanilide; Benzoyl-L-tyrosyl-p-nitroanilide; Bz-Tyrosine pNA; L-N-Benzoyltyrosine p-nitroanilide; Bz-Tyr-PNA; Bz-Tyr-4-NA
EINECS	Contact for details

Quality Control

Our Bz-Tyr-Pna is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of optical rotation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.