Description

Sinomenine Hydrochloride is a bioactive alkaloid salt derived from the Chinese medicinal plant *Sinomenium acutum*. This compound serves as a critical intermediate and reference standard in pharmaceutical research and development, particularly for its anti-inflammatory and immunosuppressive properties. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical sectors who require high-purity, well-characterized chemical entities for drug discovery and quality control.

Application

• Pharmaceutical intermediate for the synthesis of novel anti-inflammatory and immunosuppressive agents.
• Reference standard for analytical methods, including HPLC and mass spectrometry, in quality control laboratories.
• Active pharmaceutical ingredient (API) research for the development of treatments for rheumatoid arthritis and autoimmune disorders.
• Biochemical research tool for studying cellular signaling pathways related to inflammation and immune response.
• Key starting material in the preparation of derivatives for structure-activity relationship (SAR) studies.
• Component in the development of traditional Chinese medicine (TCM) formulations and modern herbal extracts.

Basic Information

Product Name	Sinomenine Hydrochloride
CAS No.	6080-33-7
Molecular Formula	C19H23NO4·HCl
Molecular Weight	365.85 g/mol
Synonyms	Cocculine Hydrochloride; Sinomenin Hydrochloride; (9α,13α,14α)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one Hydrochloride; Kukoline Hydrochloride; Cucoline Hydrochloride; Sinomenium acutum alkaloid hydrochloride
EINECS	Contact for details

Quality Control

Our Sinomenine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from methods such as HPLC, IR spectroscopy, and titration. The product meets high-purity standards suitable for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.