Description

Berbamine Dihydrochloride is a high-purity, bioactive alkaloid salt derived from natural sources, valued for its significant pharmacological research potential. This compound is a critical reference standard and intermediate for developing novel therapeutic agents, particularly in oncology and immunology research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-value fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and bioactive compound for studying anti-cancer, anti-inflammatory, and immunomodulatory mechanisms.
• Preclinical Studies: Used in in vitro and in vivo models to investigate efficacy, pharmacokinetics, and toxicity profiles.
• Fine Chemical Synthesis: Acts as a crucial intermediate or starting material for the synthesis of more complex drug candidates and derivatives.
• Biochemical Assays: Employed as a specific inhibitor or modulator in high-throughput screening and target validation studies.
• Academic Research: Supports fundamental research in natural product chemistry, medicinal chemistry, and cell biology.
• Quality Control Laboratories: Used as an analytical reference standard for the identification and quantification of berbamine in raw materials and finished products.

Basic Information

Product Name	Berbamine Dihydrochloride
CAS No.	6078-17-7
Molecular Formula	C37H40N2O6 • 2HCl
Molecular Weight	689.65 g/mol
Synonyms	Berbamine HCl; Berbamine Hydrochloride; NSC 136491; 6,6',7-Trimethoxy-2,2'-dimethylberbaman-12-ol Dihydrochloride; (1'R,12'S)-2,2'-Dimethyl-6,6',7-trimethoxy-12'-hydroxyberbaman-13'-ium Chloride; Berbaman-12-ol, 2,2'-dimethyl-6,6',7-trimethoxy-, hydrochloride (1:2), (1'R,12'S)-; Natural Berbamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our Berbamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.