Description

(1R,2S)-1-Hydroxypropane-1,2,3-Tricarboxylic Acid CAS NO 6061-97-8 is a high-purity, stereochemically defined derivative of citric acid. This specific enantiomer is valued for its role as a chiral building block and complexing agent in advanced chemical synthesis. It is essential for manufacturers in the pharmaceutical, fine chemical, and specialty chelator industries who require precise molecular configuration and consistent quality for critical processes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic agents.
• Asymmetric Catalyst Ligand: Used in the development of metal-organic frameworks (MOFs) and chiral catalysts for enantioselective synthesis.
• Specialty Chelating Agent: Functions as a selective complexing agent for metal ions in analytical chemistry and industrial cleaning formulations.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway research.
• Food & Beverage Additive (FCC Grade): Acts as a sequestrant and acidity regulator in specialized food processing applications.
• Cosmetic Ingredient: Used in stabilizing and buffering systems for high-end personal care products.

Basic Information

Product Name	(1R,2S)-1-Hydroxypropane-1,2,3-Tricarboxylic Acid
CAS No.	6061-97-8
Molecular Formula	C6H8O7
Molecular Weight	192.12 g/mol
Synonyms	(1R,2S)-1-Hydroxy-1,2,3-propanetricarboxylic Acid; (1R,2S)-Hydroxycitric Acid; (-)-Hydroxycitric Acid; Garcinia Acid; HCA; (2S,3R)-1,2,3-Trihydroxy-1,2,3-propanetricarboxylic Acid; Citric Acid, 1-Hydroxy-; 6061-97-8
EINECS	227-953-4

Quality Control

Our (1R,2S)-1-Hydroxypropane-1,2,3-Tricarboxylic Acid is manufactured under strict quality management systems. We offer material compliant with Food Chemicals Codex (FCC) and pharmaceutical-grade standards, supported by comprehensive analytical testing. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every batch to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent caking and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	-2.0° to -4.0° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.