Description

n-Succinyl-5-Aminoimidazole-4-Carboxamide Ribose 5'-Phosphate Dibarium Salt is a key biochemical intermediate in the purine nucleotide biosynthesis pathway. This compound matters for its critical role in research and development within life sciences, particularly in the study of nucleotide metabolism and enzyme kinetics. It is primarily needed by pharmaceutical R&D teams, academic biochemistry laboratories, and manufacturers of high-purity biochemical reagents.

Application

• Biochemical Research: Essential as a substrate or intermediate in enzymatic studies of the purine biosynthesis pathway, particularly for AICAR transformylase/IMP cyclohydrolase (ATIC).
• Pharmaceutical Development: Used in the research and synthesis of novel compounds targeting metabolic disorders and cancer, where nucleotide metabolism is a therapeutic focus.
• Enzyme Assay Kits: A critical component in diagnostic and research kits designed to measure enzyme activity related to purine metabolism.
• Metabolomics Studies: Serves as a standard or reference compound in mass spectrometry and chromatography for quantifying metabolic flux in biological systems.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research in biochemistry, molecular biology, and cellular metabolism.
• Precursor Synthesis: Acts as a building block in the chemical or enzymatic synthesis of more complex nucleotides and their analogs.

Basic Information

Product Name	n-Succinyl-5-Aminoimidazole-4-Carboxamide Ribose 5'-Phosphate Dibarium Salt
CAS No.	6057-44-9
Molecular Formula	C14H16BaN4O12P • xH2O (anhydrous basis)
Molecular Weight	Contact for details
Synonyms	SAICAR Barium Salt; 5'-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole Barium Salt; 5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)imidazole-4-carboxamide, N-succinyl-, Barium Salt; Barium SAICAR; NSC 403178; AICAR Succinyl Phosphate Barium Salt; 5'-Phosphoribosyl-5-amino-4-imidazole-N-succinocarboxamide Barium Salt
EINECS	Contact for details

Quality Control

Our n-Succinyl-5-Aminoimidazole-4-Carboxamide Ribose 5'-Phosphate Dibarium Salt is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Barium Content	Conforms to theoretical
Solubility	Soluble in water, insoluble in organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.