Description

Harmalol Hcl is a high-purity alkaloid hydrochloride salt derived from *Peganum harmala* and related species. This compound serves as a critical reference standard and key intermediate in pharmaceutical research and development, particularly for its biochemical activity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, well-characterized compounds for analytical and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and pharmaceutical formulations in quality control laboratories.
• Biochemical Research: Serves as a tool compound in enzymatic studies and receptor binding assays due to its known pharmacological profile.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis and development of more complex therapeutic agents.
• Analytical Chemistry: Acts as a calibration standard in chromatographic methods (HPLC, LC-MS) for method development and validation.
• Natural Product Isolation & Standardization: Used to standardize plant-derived extracts and nutraceutical products.
• Academic Research: Fundamental studies in pharmacology, phytochemistry, and medicinal chemistry.

Basic Information

Product Name	Harmalol Hcl
CAS No.	6028-07-5
Molecular Formula	C13H15N2O•HCl
Molecular Weight	248.73 g/mol
Synonyms	Harmalol hydrochloride; 1-Methyl-4,9-dihydro-3H-β-carbolin-7-ol hydrochloride; 4,9-Dihydro-1-methyl-3H-pyrido[3,4-b]indol-7-ol hydrochloride; Harmalol HCl; 7-Hydroxy-1-methyl-1,2,3,4-tetrahydro-β-carboline hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Harmalol Hcl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research and development. A Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to brownish powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.