Description

Harmalol Hydrochloride Dihydrate is a high-purity, pharmacologically active alkaloid derivative. This compound is valued for its role as a critical reference standard and intermediate in pharmaceutical research and development. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in neuropharmacology, metabolic studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of harmala alkaloids in research and quality control laboratories.
• Biochemical Research: Serves as a key reagent in studies investigating monoamine oxidase (MAO) inhibition, receptor binding, and other neurological pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis and development of potential therapeutic compounds targeting neurological and psychiatric conditions.
• Analytical Chemistry: Functions as a calibration standard for method development and validation in chromatographic systems.
• Natural Product Isolation & Standardization: Acts as a benchmark for the identification and quantification of Harmalol in plant extracts, such as those from *Peganum harmala*.

Basic Information

Product Name	Harmalol Hydrochloride Dihydrate
CAS No.	6028-00-8
Molecular Formula	C13H14N2O • HCl • 2H2O
Molecular Weight	284.73 g/mol
Synonyms	1-Methyl-4,9-dihydro-3H-β-carbolin-7-ol hydrochloride dihydrate; Harmalol HCl dihydrate; 7-Hydroxy-1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole hydrochloride dihydrate; Harmalol hydrochloride hydrate; Harmalol HCL 2H2O
EINECS	Contact for details

Quality Control

Our Harmalol Hydrochloride Dihydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	Theoretical (Dihydrate)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.