Description

Carboxyaminoimidazole Ribotide is a key biochemical intermediate in the *de novo* purine biosynthesis pathway. This compound matters for its critical role in nucleotide metabolism, making it an essential building block for research and development in life sciences. It is primarily needed by pharmaceutical researchers, biotechnology companies, and academic institutions focused on metabolic studies, enzyme kinetics, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a critical substrate and intermediate in studies of purine biosynthesis and nucleotide metabolism.
• Enzymology Studies: Serves as a standard or reagent for investigating the activity of enzymes like AIR carboxylase (PurE) within the IMP synthesis pathway.
• Pharmaceutical Development: Acts as a reference compound in the research and screening of potential inhibitors targeting purine metabolism for therapeutic applications.
• Metabolic Pathway Analysis: Employed in *in vitro* assays to trace and quantify metabolic flux in cellular systems.
• Academic & Educational Use: Supplied as a high-purity biochemical for university laboratories and teaching institutions.
• Diagnostic Reagent Manufacturing: Potential use as a component in specialized diagnostic kits for metabolic disorders.

Basic Information

Product Name	Carboxyaminoimidazole Ribotide
CAS No.	6001-14-5
Molecular Formula	C11H15N4O10P
Molecular Weight	394.23 g/mol
Synonyms	5-Amino-1-(5-O-Phosphono-β-D-ribofuranosyl)imidazole-4-carboxylic Acid; 5-Amino-1-(5-Phospho-β-D-ribofuranosyl)imidazole-4-carboxylate; 5-Aminoimidazole Ribonucleotide Carboxylic Acid; CAIR; 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxylic Acid; 5'-Phosphoribosyl-5-amino-4-imidazolecarboxylic Acid; 5-Amino-4-imidazolecarboxylic Acid Ribotide; AIR Carboxylate.
EINECS	Contact for details

Quality Control

Our Carboxyaminoimidazole Ribotide is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for biochemical and pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.