Description

N,N'-Diisopropylcarbodiimide (CAS NO 693-13-0) is a versatile and highly effective coupling agent widely used in organic synthesis. Its primary value lies in its ability to facilitate the formation of amide bonds, a critical reaction in the production of peptides, pharmaceuticals, and other fine chemicals. This makes it an essential reagent for research institutions, pharmaceutical manufacturers, and fine chemical producers seeking efficient and reliable synthesis pathways.

Application

• Peptide Synthesis: As a key coupling reagent (DIC) in solid-phase and solution-phase peptide synthesis to activate carboxylic acids.
• Pharmaceutical Intermediates: For the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules requiring amide bond formation.
• Polymer Chemistry: Used in the production of polyamides, polyurethanes, and other specialty polymers.
• Bioconjugation: Facilitating the linkage of biomolecules, such as proteins and antibodies, with other molecules for diagnostic and therapeutic applications.
• Agrochemical Synthesis: In the manufacture of herbicides, fungicides, and insecticides that contain amide functional groups.
• Material Science: For surface modification and the creation of advanced materials with specific functional properties.

Basic Information

Product Name	N,N'-Diisopropylcarbodiimide
CAS No.	693-13-0
Molecular Formula	C7H14N2
Molecular Weight	126.20 g/mol
Synonyms	DIC; Diisopropylcarbodiimide; N,N'-Diisopropylcarbodiimide; 1,3-Diisopropylcarbodiimide; DIPC; N,N'-Di-iso-propylcarbodiimide; Carbonyldiisopropylimide; Isopropylcarbodiimide
EINECS	211-743-7

Quality Control

Our N,N'-Diisopropylcarbodiimide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is analyzed to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Diisopropylamine (GC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.