Description

β-Cortol is a key steroid metabolite and intermediate of significant interest in pharmaceutical research and development. This compound is valued for its role in the study of cortisol metabolism and as a critical building block for synthesizing more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the production of corticosteroids, diagnostic agents, and reference standards for analytical testing.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of corticosteroid drugs and related therapeutic agents.
• Biochemical Research: Used as a reference standard and metabolite in studies investigating adrenal cortex function and steroid hormone pathways.
• Diagnostic Reagent Manufacturing: Serves as a raw material in the production of reagents for clinical assays measuring cortisol and its metabolites.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control (QC) of steroid-containing products via HPLC, GC-MS, or LC-MS.
• Fine Chemical Synthesis: Acts as a specialized starting material for the custom synthesis of novel steroid derivatives for pharmacological evaluation.

Basic Information

Product Name	β-Cortol
CAS No.	667-65-2
Molecular Formula	C21H34O5
Molecular Weight	366.50 g/mol
Synonyms	5β-Pregnane-3α,11β,17α,20β,21-Pentol; (3α,5β,11β,17α,20β)-3,11,17,20,21-Pentahydroxypregnane; 20β-Hydroxycortisol; 11β,17α,20β,21-Tetrahydroxypregnane-3-one; β-Cortol; Cortol, β-
EINECS	Contact for details

Quality Control

Our β-Cortol is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, assay, and impurity profiles. For specific project requirements, we can supply material that aligns with in-house specifications or discuss custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.