Description

2'-Deoxyadenosine 5'-Phosphate is a vital nucleotide monophosphate, serving as a fundamental building block in molecular biology and biochemistry. Its primary value lies in its role as a precursor for DNA synthesis and as a critical reagent in enzymatic studies and diagnostic assays. This high-purity biochemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic industries, particularly for applications in oligonucleotide synthesis, PCR, and enzyme kinetics.

Application

• Oligonucleotide & DNA Synthesis: A key phosphoramidite precursor for solid-phase synthesis of primers, probes, and gene fragments.
• Enzymology & Biochemical Research: Substrate for studies involving DNA polymerases, kinases, and other nucleotide-metabolizing enzymes.
• Diagnostic Assay Development: Used in the formulation of reagents for molecular diagnostics, including PCR and next-generation sequencing (NGS) platforms.
• Pharmaceutical Intermediate: Serves as a starting material or intermediate in the synthesis of nucleotide-based antiviral or anticancer therapeutics.
• Cell Culture & Media Supplement: Component in specialized cell culture media for certain metabolic studies.
• Reference Standard: High-purity grade material for use as an analytical standard in quality control laboratories.

Basic Information

Product Name	2'-Deoxyadenosine 5'-Phosphate
CAS No.	653-63-4
Molecular Formula	C10H14N5O6P
Molecular Weight	331.22 g/mol
Synonyms	dAMP; 2'-Deoxyadenosine 5'-Monophosphate; Deoxyadenylic Acid; Deoxyadenosine Monophosphate; 5'-dAMP; Adenine Deoxyribonucleotide; 5'-O-Phosphonodeoxyadenosine; (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl Dihydrogen Phosphate
EINECS	211-500-1

Quality Control

Our 2'-Deoxyadenosine 5'-Phosphate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake. For extended storage under inert atmosphere, contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 3.0%
pH (1% Solution)	2.0 - 4.0
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.