Description

21α-Hydroxy-12-Methoxyajmalan-17-One CAS NO 639-28-1 is a complex indole alkaloid derivative, structurally related to the ajmaline family. This specialized compound serves as a critical advanced intermediate and reference standard in the research and development of novel pharmaceutical agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthetic chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex bioactive molecules and potential drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies targeting cardiovascular or neurological pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, or NMR analysis.
• Biochemical Research: Employed in studies investigating the biological activity and mechanism of action of ajmaline-related alkaloids.
• Academic Synthesis: Used in university and institutional laboratories for teaching and research in advanced organic synthesis techniques.
• Process Development: Acts as a critical material for scaling up and optimizing synthetic routes in pilot plant and kilo-lab environments.

Basic Information

Product Name	21α-Hydroxy-12-Methoxyajmalan-17-One
CAS No.	639-28-1
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	21α-Hydroxy-12-methoxyajmalan-17-one; 12-Methoxy-21α-hydroxyajmalan-17-one; Ajmaline derivative; (17R,21α)-17-Hydroxy-12-methoxyajmalan-21-one; 17-Oxo-12-methoxyajmalan-21α-ol
EINECS	Contact for details

Quality Control

Our 21α-Hydroxy-12-Methoxyajmalan-17-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Our quality system is designed to meet the stringent demands of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.