Description

Oleic Acid-[9,10-3H] CAS NO 636-34-0 is a high-specific-activity, tritium-labeled form of the common monounsaturated fatty acid, oleic acid. This radiolabeled compound is an indispensable tool for tracing metabolic pathways, studying lipid biochemistry, and conducting precise pharmacokinetic research. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for advanced analytical applications.

Application

• Biochemical Research: As a tracer for investigating fatty acid metabolism, β-oxidation, and lipid biosynthesis pathways in vivo and in vitro.
• Pharmaceutical Development: For conducting absorption, distribution, metabolism, and excretion (ADME) studies of lipid-based drug formulations.
• Diagnostic Agent Development: In the research and quality control of radiopharmaceuticals and diagnostic imaging agents.
• Metabolic Studies: To trace the incorporation of oleic acid into complex lipids like triglycerides, phospholipids, and cholesteryl esters.
• Enzyme Assays: As a substrate for studying the activity of lipases, desaturases, and other lipid-modifying enzymes.
• Membrane Biology: For researching lipid dynamics, membrane fluidity, and receptor-ligand interactions in cell membranes.

Basic Information

Product Name	Oleic Acid-[9,10-3H]
CAS No.	636-34-0
Molecular Formula	C18H34O2 (³H labeled)
Molecular Weight	~282.5 g/mol (varies with specific activity)
Synonyms	(Z)-Octadec-9-enoic acid-[9,10-³H]; 9-Octadecenoic acid (9Z)-, labeled with tritium; cis-9-Octadecenoic acid-[9,10-³H]; Tritiated oleic acid; [9,10-³H]-Oleic Acid; ³H-Oleic Acid; Oleic Acid (tritiated); Red oil (labeled)
EINECS	211-281-5 (for unlabeled Oleic Acid)

Quality Control

Every batch of Oleic Acid-[9,10-3H] is manufactured and analyzed under strict quality systems to ensure traceability, purity, and specified radioactive concentration. Quality is verified through rigorous analytical techniques including radiochemical purity analysis by HPLC or TLC, specific activity determination, and chemical identity confirmation. A comprehensive Certificate of Analysis (COA) detailing batch-specific data—including purity, specific activity, solvent, and expiration date—is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in the original solvent as specified on the label. Due to its nature as an easily oxidized (store under inert atmosphere) compound and a radiochemical, it must be handled with appropriate shielding and in accordance with local radiation safety regulations. Keep away from heat and ignition sources.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity	≥ 97%
Specific Activity	10-100 Ci/mmol (Contact for specific value)
Concentration	1 mCi/mL in ethanol (or as specified)
Identification (IR/NMR)	Conforms to structure
Solvent	Ethanol, Toluene, or as customized

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.