Description

D-Desthiobiotin is a key intermediate and derivative of biotin, a vital water-soluble B-complex vitamin. This compound is essential for research and development in biochemistry and pharmaceutical synthesis, particularly in studying biotin-dependent enzymes and metabolic pathways. It is primarily utilized by manufacturers and researchers in the pharmaceutical, nutraceutical, and life science industries for the production of advanced biochemical reagents and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of biotin analogs, prodrugs, and other high-value pharmaceutical compounds.
• Biochemical Research: Used as a research tool in enzymology to study the mechanisms of biotin-dependent carboxylases and other enzymes.
• Cell Culture & Microbiology: Serves as a defined growth factor or supplement in specialized cell culture media and microbiological studies.
• Diagnostic Reagent Production: Employed in the manufacturing of diagnostic kits and assays that utilize biotin-streptavidin binding technology.
• Nutraceutical Development: Acts as a precursor or intermediate in the development of advanced vitamin supplements and fortified products.
• Chemical Synthesis: Used as a chiral starting material or intermediate in asymmetric synthesis and fine chemical manufacturing.

Basic Information

Product Name	D-Desthiobiotin
CAS No.	636-20-4
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	D-Desthiobiotin; (+)-Desthiobiotin; D-α-(5,6-cis-Dihydro-2-oxo-1H-thieno[3,4-d]imidazol-6-yl)valeric Acid (desthiobiotin form); (3aS,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric Acid (desthiobiotin form); Biotin Desthio; Desthiobiotin; Vitamin H Desthio Derivative
EINECS	211-267-5

Quality Control

Our D-Desthiobiotin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: +40° to +50° (c=1 in 0.1N NaOH)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.