Description

Bilirubin CAS NO 635-65-4 is a yellow-orange tetrapyrrole bile pigment and a key catabolite of heme. It serves as a critical biomarker for liver function and hemolytic conditions in clinical diagnostics. This high-purity biochemical is essential for manufacturers of in-vitro diagnostic (IVD) reagents, research chemicals, and calibrator/control solutions used in laboratory and medical settings.

Application

• Clinical Diagnostic Reagents: Primary standard for calibrating bilirubin assays in automated chemistry analyzers.
• Biochemical Research: Used as a substrate or standard in studies of heme metabolism, liver function, and antioxidant mechanisms.
• Quality Control Materials: A key component in the production of quality control sera and calibrators for laboratory proficiency testing.
• Pharmaceutical Intermediates: Serves as a starting material or reference compound in pharmaceutical research and development.
• Enzyme Activity Assays: Employed in assays measuring the activity of enzymes like biliverdin reductase.

Basic Information

Product Name	Bilirubin
CAS No.	635-65-4
Molecular Formula	C33H36N4O6
Molecular Weight	584.66 g/mol
Synonyms	1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropanoic acid; Cholerythrin; Hematoidin; Bilirubin IXα; NSC 2199; Urobilin; Bilirubin (natural); 4,15-Biladiene-ac-8,12-dipropionic acid
EINECS	211-239-7

Quality Control

Our Bilirubin is produced and tested under a strict quality management system to ensure batch-to-batch consistency and reliability for critical diagnostic and research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and relevant impurities. We can supply material compliant with specifications for use as a primary reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to reddish-brown powder or crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Practically insoluble in water; soluble in chloroform, dimethyl sulfoxide, and dilute alkali solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.