Description

Berberine Acid Sulfate is a quaternary ammonium salt derived from the alkaloid berberine, widely recognized for its biological activity. This high-purity compound is essential for research and development in the pharmaceutical and nutraceutical sectors, where consistent quality and reliable supply are paramount. It serves as a critical raw material for manufacturers developing products in metabolic health, antimicrobial applications, and traditional medicine formulations.

Application

• Pharmaceutical intermediate for the synthesis of anti-diabetic and cardiovascular drugs.
• Key active ingredient in dietary supplements targeting metabolic syndrome and blood sugar management.
• Reference standard and biochemical reagent for analytical testing and pharmacological research.
• Starting material for the development of antimicrobial and anti-inflammatory formulations.
• Component in veterinary medicine products for gastrointestinal and infectious ailments.
• Raw material for the standardization of herbal extracts in the nutraceutical industry.

Basic Information

Product Name	Berberine Acid Sulfate
CAS No.	633-66-9
Molecular Formula	C20H18NO4 · H2SO4
Molecular Weight	433.43 g/mol
Synonyms	Berberine Sulfate; Berberine Bisulfate; Berberine Hydrogen Sulfate; Natural Yellow 18 sulfate; Umbellatine sulfate; 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium sulfate
EINECS	211-195-9

Quality Control

Our Berberine Acid Sulfate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is tested against rigorous in-house specifications, which may include compliance with relevant sections of pharmacopeial standards (e.g., USP, EP) for identification, assay, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, heavy metals, residual solvents, and microbiological data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.