Description

Corynoxeine CAS NO 630-94-4 is a natural indole alkaloid compound derived from the *Uncaria* genus of plants, known for its distinct pharmacological profile. This high-purity reference standard is essential for research and development in the pharmaceutical and nutraceutical sectors, where precise chemical identity and activity are paramount. It is primarily sought by scientists and manufacturers focused on neurological and cardiovascular research, as well as quality control laboratories requiring authenticated materials for analytical testing.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of related herbal extracts and finished products in quality control laboratories.
• Neurological Research: Investigated for its potential biological activity related to neuroprotection and as a modulator of dopaminergic systems in preclinical studies.
• Natural Product Isolation & Synthesis: Serves as a key intermediate or target molecule in the semi-synthesis of more complex alkaloids and for structure-activity relationship (SAR) studies.
• Analytical Method Development: Employed as a standard to develop and validate analytical methods such as HPLC, LC-MS, and TLC for the quantification of *Uncaria* (Cat's Claw) constituents.
• Dietary Supplement Authentication: Used to authenticate and standardize Cat's Claw extracts, ensuring product potency, consistency, and compliance with label claims.
• Academic & Clinical Research: Supports fundamental research into the chemistry and bioactivity of plant-derived indole alkaloids.

Basic Information

Product Name	Corynoxeine
CAS No.	630-94-4
Molecular Formula	C22H26N2O4
Molecular Weight	382.46 g/mol
Synonyms	Corynoxeine; (19E)-Corynoxeine; NSC 169915; 16,17-Didehydro-17-methoxy-19α-methyloxayohimban-16-carboxylic acid methyl ester; 19α-Hydroxy-17-methoxy-19-methyl-16,17-didehydrooxayohimban-16-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Corynoxeine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.