Description

(R)-3-Hydroxybutyric Acid CAS NO 625-72-9 is the (R)-enantiomer of 3-hydroxybutyric acid, a key chiral intermediate and a naturally occurring metabolite. This high-purity stereoisomer is essential for applications requiring specific optical activity, such as in the synthesis of advanced pharmaceuticals and fine chemicals. It serves critical roles in the research and production of chiral drugs, nutraceuticals, and as a biochemical standard in metabolic studies for the pharmaceutical, biotechnology, and academic research sectors.

Application

• Chiral Pharmaceutical Synthesis: A crucial building block for the production of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in cardiovascular and metabolic disorder treatments.
• Biochemical Research & Standards: Used as a reference standard in analytical methods (HPLC, GC-MS) and in metabolic pathway studies, especially related to ketone body metabolism.
• Nutraceutical & Cosmetic Intermediates: An intermediate in the synthesis of high-value ingredients for dietary supplements and advanced skincare formulations.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis to create other valuable enantiopure compounds.
• Polymer Science: A monomer for the synthesis of biodegradable, chiral polyhydroxyalkanoates (PHAs) with specialized properties.

Basic Information

Item	Details
Product Name	(R)-3-Hydroxybutyric Acid
CAS No.	625-72-9
Molecular Formula	C4H8O3
Molecular Weight	104.10 g/mol
Synonyms	(R)-3-Hydroxybutanoic Acid; D-(-)-3-Hydroxybutyric Acid; (R)-(-)-3-Hydroxybutyric Acid; (3R)-3-Hydroxybutanoic Acid; D-β-Hydroxybutyric Acid; (R)-BHB; R-3-HB; R-3-Hydroxybutyrate; D-3-Hydroxybutyric Acid
EINECS	210-909-5

Quality Control

Our (R)-3-Hydroxybutyric Acid is manufactured under a strict quality management system. Each batch is tested to ensure high chemical and optical purity, with specifications typically meeting or exceeding standards for research and pharmaceutical intermediate use. Comprehensive testing includes chiral purity assay, identification, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (R-enantiomer)
Melting Point	44 - 48 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.