Description

Thiocholine is a critical biochemical reagent and synthetic intermediate, primarily recognized for its role in enzymatic assays and neurochemical research. Its unique structure makes it an essential substrate for cholinesterase enzymes, enabling precise measurement of enzyme activity in diagnostic and research settings. This compound is vital for pharmaceutical R&D, clinical diagnostics, and academic laboratories focused on neuroscience and toxicology.

Application

• Enzyme Substrate for Cholinesterase Assays: Primary substrate for colorimetric and electrochemical detection of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity.
• Biosensor Development: Key component in the fabrication of amperometric biosensors for the detection of organophosphorus pesticides and nerve agents.
• Neurochemical Research: Used in studies investigating cholinergic system function, neurotransmission, and the effects of neuroactive compounds.
• Pharmaceutical Testing: Employed in high-throughput screening (HTS) platforms to evaluate potential drugs targeting cholinesterases for conditions like Alzheimer's disease.
• Toxicology and Environmental Monitoring: Integral to assays that measure exposure to cholinesterase-inhibiting chemicals in environmental and occupational health studies.
• Diagnostic Reagent Manufacturing: Serves as a raw material in producing diagnostic kits for liver function and pesticide exposure.

Basic Information

Item	Details
Product Name	Thiocholine
CAS No.	625-00-3
Molecular Formula	C5H14NS+
Molecular Weight	120.24 g/mol
Synonyms	2-Mercaptoethyltrimethylammonium; (2-Mercaptoethyl)trimethylammonium; Thiocholine cation; S-(2-Trimethylammonio)ethanethiol; Thiocholine ion; Choline, thio-; Ethanethiol, 2-(trimethylammonio)-
EINECS	210-868-6

Quality Control

Our Thiocholine is produced under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.