Description

Chorismic Acid CAS NO 617-12-9 is a pivotal biosynthetic intermediate in the shikimate pathway, serving as a key branch-point metabolite. Its primary commercial value lies in its role as the direct precursor for the synthesis of essential aromatic amino acids, vitamins, and numerous secondary metabolites. This compound is therefore critically needed by research institutions, pharmaceutical developers, and biotechnology companies focused on metabolic engineering, antibiotic development, and biochemical pathway analysis.

Application

• Biochemical Research & Pathway Studies: Essential for in vitro studies of the shikimate pathway, enzyme kinetics, and inhibition assays.
• Pharmaceutical Intermediate: Serves as a key starting material or reference standard in the research and development of novel antibiotics and antimicrobial agents that target bacterial aromatic amino acid synthesis.
• Metabolic Engineering: Used as a supplement or standard in microbial fermentation processes aimed at optimizing the production of high-value compounds like L-tryptophan, L-phenylalanine, L-tyrosine, and folate.
• Enzyme Substrate: Critical substrate for enzymes such as chorismate mutase, anthranilate synthase, and isochorismate synthase in functional characterization and high-throughput screening.
• Reference Standard: High-purity grade is used as an analytical reference standard in HPLC, LC-MS, and NMR for quality control in related bioprocesses.
• Agrochemical Research: Investigated in the development of herbicides that disrupt the shikimate pathway, which is absent in animals.

Basic Information

Product Name	Chorismic Acid
CAS No.	617-12-9
Molecular Formula	C10H10O6
Molecular Weight	226.18 g/mol
Synonyms	Chorismate; (3R,4R)-3-[(1-Carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic Acid; 3-[(1-Carboxyvinyl)oxy]-4-hydroxy-1,5-cyclohexadiene-1-carboxylic Acid; Chorismic Acid Barium Salt; O-(1-Carboxyvinyl)-3-enolpyruvylshikimic Acid
EINECS	210-518-8

Quality Control

Our Chorismic Acid is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.