Description

(-)-Synephrine CAS NO 614-35-7 is a chiral, naturally occurring alkaloid known for its sympathomimetic activity. This high-purity compound is critical for applications demanding precise stereochemistry and consistent biological activity. It serves as a key intermediate and reference standard for pharmaceutical research, nutraceutical development, and analytical laboratories worldwide.

Application

• Pharmaceutical Intermediate: Synthesis of adrenergic agents and other active pharmaceutical ingredients (APIs).
• Reference Standard: For quality control and analytical method development in HPLC, LC-MS, and chiral separation techniques.
• Nutraceutical & Dietary Supplement Formulation: As a bioactive ingredient in weight management and energy support products.
• Biochemical Research: Studying α-adrenergic and β-adrenergic receptor interactions and metabolic pathways.
• Cosmetic Applications: Incorporated into topical formulations for its potential skin-firming properties.
• Veterinary Medicine: Used in research for developing treatments in animal health.

Basic Information

Product Name	(-)-Synephrine
CAS No.	614-35-7
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	L-Synephrine; (-)-p-Synephrine; (R)-(-)-Synephrine; Oxedrine; Sympathol; p-Synephrine; 4-[1-Hydroxy-2-(methylamino)ethyl]phenol; 1-(4-Hydroxyphenyl)-2-(methylamino)ethanol; Citrus aurantium extract (primary alkaloid)
EINECS	210-377-6

Quality Control

Our (-)-Synephrine is manufactured under strict quality management systems. Each batch is tested to ensure high chiral purity and meets stringent specifications for pharmaceutical and nutraceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and residual solvents is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (-)-Isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.