Description

(-)-Manthine CAS NO 606-51-9 is a specific stereoisomer of the manthine alkaloid, a compound of significant interest in organic synthesis and pharmaceutical research. Its defined stereochemistry makes it a valuable chiral building block and reference standard for developing active pharmaceutical ingredients (APIs) and other fine chemicals. This high-purity compound is essential for research and development laboratories, pharmaceutical manufacturers, and advanced chemical synthesis operations seeking precise molecular control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Chemical Research & Development: Used as a reference standard and building block in organic synthesis for method development and novel compound creation.
• Asymmetric Catalysis: Employed as a ligand or substrate in catalytic reactions to induce stereoselectivity.
• Natural Product Synthesis: A critical component in the total synthesis of complex natural alkaloids and related compounds.
• Analytical Standard: Provides a high-purity benchmark for analytical method validation, including HPLC, GC, and NMR analysis in quality control laboratories.

Basic Information

Product Name	(-)-Manthine
CAS No.	606-51-9
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	(-)-Manthine; (S)-Manthine; L-Manthine; (S)-2-(Dimethylaminomethyl)-1,3-benzodioxole; 1,3-Benzodioxole-5-methanamine, N,α-dimethyl-, (S)-; Manthine; 606-51-9
EINECS	Contact for details

Quality Control

Our (-)-Manthine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH limits
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.