Description

Demeclocycline Hydrochloride CAS NO 64-73-3 is a semi-synthetic tetracycline antibiotic derived from a strain of *Streptomyces aureofaciens*. This compound is valued for its broad-spectrum antibacterial activity, primarily functioning as a protein synthesis inhibitor. It is a critical active pharmaceutical ingredient (API) for the formulation of specific antibiotic medications and is also utilized in biochemical research. Industries requiring this high-purity compound include pharmaceutical manufacturing, veterinary medicine, and life science research laboratories.

Application

• Pharmaceutical API: Primary use as the active ingredient in antibiotic formulations for human and veterinary use.
• Biomedical Research: Used as a tool compound in microbiological studies to investigate bacterial protein synthesis and antibiotic resistance mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Veterinary Medicine: Incorporated into treatments for bacterial infections in livestock and companion animals.

Basic Information

Product Name	Demeclocycline Hydrochloride
CAS No.	64-73-3
Molecular Formula	C21H21ClN2O8 • HCl
Molecular Weight	501.31 g/mol
Synonyms	Demethylchlortetracycline Hydrochloride; 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride; Declomycin; Ledermycin; DMCT HCl; Clortetrin; Detravis
EINECS	200-597-0

Quality Control

Our Demeclocycline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing parameters such as assay, purity, and identification. Our quality commitment aligns with cGMP principles to ensure supply reliability and regulatory compliance for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to light yellow, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.