Description

Iodoacetic Acid is a versatile alkylating agent and a key biochemical reagent used to modify proteins and enzymes. This compound is particularly valued for its role in selectively blocking cysteine residues, making it an essential tool in proteomics research and biochemical studies. It serves critical functions in pharmaceutical research, life science laboratories, and as a synthetic intermediate for fine chemicals.

Application

• Biochemical Research: As a potent alkylating agent for the selective modification of cysteine sulfhydryl groups in proteins and enzymes.
• Proteomics & Enzyme Studies: Used to investigate enzyme active sites, protein structure, and function through targeted inhibition.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex organic molecules and active pharmaceutical ingredients (APIs).
• Metabolic Pathway Analysis: Employed to inhibit glycolysis by targeting glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in cellular studies.
• Cross-linking Agent: Utilized in the preparation of modified biomaterials and conjugates for diagnostic applications.
• Organic Synthesis: Acts as a reagent for introducing the iodoacetyl functional group into target molecules.

Basic Information

Product Name	Iodoacetic Acid
CAS No.	64-69-7
Molecular Formula	C2H3IO2
Molecular Weight	185.95 g/mol
Synonyms	Iodoethanoic Acid; 2-Iodoacetic Acid; Monoiodoacetic Acid; IAA; Iodoacetate; Acetic Acid, Iodo-; Glycolic Acid, Iodo-; (Iodoacetyl)hydroxy
EINECS	200-590-1

Quality Control

Our Iodoacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity standards suitable for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	80°C - 83°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.