Description

Veratrine is a complex mixture of alkaloids, primarily cevadine and veratridine, extracted from plants of the *Schoenocaulon* and *Veratrum* genera. This potent compound is valued for its significant biological activity, particularly as a sodium channel agonist, making it a crucial tool in neurological and pharmacological research. It is essential for researchers and manufacturers in the life sciences sector, especially those developing neuroactive agents, studying ion channel function, or producing reference standards for analytical testing.

Application

• Neurological Research: As a classic sodium channel activator (agonist) used to study channel gating mechanisms, neuronal excitability, and action potential generation.
• Pharmacological Studies: Employed in the development and screening of novel neuroprotective agents, anesthetics, and anticonvulsants by modulating sodium channel activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical development and for calibrating equipment in toxicology labs.
• Biochemical Reagent: Used in cell-based assays and patch-clamp experiments to investigate cellular signaling pathways and membrane physiology.
• Toxicology: Applied in research related to natural toxins and the mechanisms of poisoning, aiding in the development of detection methods and antidotes.

Basic Information

Product Name	Veratrine
CAS No.	62-59-9
Molecular Formula	Mixture (Primarily C32H49NO9 and C36H51NO11)
Molecular Weight	Mixture
Synonyms	Cevadine; Veratridine; Veratria; Sabadilla Alkaloids; Cevadilla Alkaloids; Schoenocaulon officinale alkaloids; Veratrum album alkaloids
EINECS	200-540-1

Quality Control

Our Veratrine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analysis, including identification by spectroscopic methods and purity assessment by HPLC. A detailed Certificate of Analysis (COA) specifying the alkaloid profile, purity, and other critical parameters is provided with every shipment to support your compliance and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white amorphous powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (Total Alkaloids by HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.