Description

Tetracycline CAS NO 60-54-8 is a broad-spectrum antibiotic belonging to the polyketide class, widely recognized for its bacteriostatic activity against a variety of Gram-positive and Gram-negative bacteria. Its primary value lies in its ability to inhibit protein synthesis, making it a critical tool in combating bacterial infections. This compound is essential for manufacturers in the pharmaceutical, veterinary medicine, and research sectors, serving as an active pharmaceutical ingredient (API) and a key reference standard.

Application

• Pharmaceutical API: Core ingredient in the formulation of human and veterinary antibiotic preparations, including tablets, capsules, and ointments.
• Veterinary Medicine: Used in feed additives and therapeutic treatments for livestock, poultry, and aquaculture to prevent and treat bacterial diseases.
• Biomedical Research: Employed as a selective agent in cell culture and molecular biology to study bacterial protein synthesis and resistance mechanisms.
• Reference Standard: Serves as a high-purity calibrant in analytical laboratories for quality control testing of pharmaceutical products.
• Agricultural Applications: Historically used for the control of certain plant bacterial pathogens, though use is now highly regulated.

Basic Information

Item	Details
Product Name	Tetracycline
CAS No.	60-54-8
Molecular Formula	C₂₂H₂₄N₂O₈
Molecular Weight	444.43 g/mol
Synonyms	Tetracycline Hydrochloride (common salt form); Abricycline; Achromycin; Ambramycin; Cyclomycin; Deschlorobiomycin; Panmycin; Polycycline; Steclin; Tetracyn; Tetramycin; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
EINECS	200-481-9

Quality Control

Our Tetracycline is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure it meets high-purity standards, with specifications potentially aligned to USP, EP, or BP monographs depending on the grade. A detailed Certificate of Analysis (COA), including results for assay, related substances, and microbiological testing, is provided to guarantee traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any individual impurity ≤ 1.0%
Specific Rotation	-240° to -255° (c=1, 0.1N HCl)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.