Description

Creatinine CAS NO 60-27-5 is a critical biochemical marker and organic compound derived from the metabolism of creatine in muscle tissue. Its reliable quantification is essential for accurate clinical diagnostics and research into renal function and muscle metabolism. This high-purity product is indispensable for manufacturers of in-vitro diagnostic (IVD) reagents, clinical chemistry calibrators, and research institutions focused on metabolic studies.

Application

• Primary Standard for Clinical Diagnostics: Used as a certified reference material (CRM) for calibrating and validating assays that measure kidney function, particularly serum and urine creatinine tests.
• In-Vitro Diagnostic (IVD) Reagent Production: A key raw material in the formulation of enzymatic and Jaffe method-based reagent kits for automated clinical analyzers.
• Biochemical Research: Employed in metabolic studies, muscle physiology research, and as a standard in analytical method development using HPLC, LC-MS, and spectroscopy.
• Quality Control in Pharmaceuticals: Used in the quality control of pharmaceutical products and as an analytical standard in compliance with pharmacopeial monographs.
• Calibrator and Control Solution Manufacturing: Essential for producing accurate calibration curves and quality control materials for clinical laboratories.

Basic Information

Product Name	Creatinine
CAS No.	60-27-5
Molecular Formula	C4H7N3O
Molecular Weight	113.12 g/mol
Synonyms	2-Amino-1-methyl-1H-imidazol-4(5H)-one; 2-Amino-1-methylimidazolin-4-one; 1-Methylglycocyamidine; 1-Methyl-2-amino-1H-imidazol-4(5H)-one; Creatinin; Kreatinin; NSC 13123
EINECS	200-466-7

Quality Control

Our Creatinine is manufactured under a strict quality management system to ensure batch-to-batch consistency and reliability for critical diagnostic applications. It is produced to meet the exacting standards required for reference materials. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is stable under these conditions but should be kept in a low-humidity environment to prevent any potential moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 0.5%
Solubility	Freely soluble in water; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.