Description

7-Ap-7-Deaza-Dgtp·3Na is a chemically modified nucleoside triphosphate analog, a critical building block for advanced molecular biology and diagnostic applications. Its primary value lies in its ability to enhance the stability and performance of nucleic acid amplification and sequencing processes. This high-purity reagent is essential for researchers and manufacturers in the fields of next-generation sequencing (NGS), PCR diagnostics, and synthetic biology.

Application

• Next-Generation Sequencing (NGS): Used as a modified dGTP analog to improve read accuracy and reduce sequencing bias in various NGS platforms.
• PCR and qPCR Assays: Enhances the specificity and efficiency of polymerase chain reactions, particularly useful in diagnostic kits for pathogen detection.
• Synthetic Biology and DNA Synthesis: Serves as a key substrate for enzymatic synthesis of modified oligonucleotides with enhanced properties.
• Forensic Analysis: Employed in specialized PCR protocols to obtain clearer genetic profiles from challenging or degraded samples.
• Antiviral Research: Investigated as a potential nucleotide analog for studying viral replication mechanisms and developing novel therapeutics.
• Biochemical Research: A vital tool for studying DNA polymerase kinetics, fidelity, and mechanisms of nucleotide incorporation.

Basic Information

Product Name	7-Ap-7-Deaza-Dgtp·3Na
CAS No.	587848-73-5
Molecular Formula	C11H14N5O13P3·3Na
Molecular Weight	Contact for details
Synonyms	7-Deaza-7-propargylamino-dGTP trisodium salt; 7-Propargylamino-7-deaza-2'-deoxyguanosine-5'-triphosphate trisodium salt; 7-Amino-propyne-7-deaza-dGTP-Na3; 7-APA-7-deaza-dGTP; Modified dGTP; 7-Alkynylamino-7-deaza-2'-deoxyguanosine triphosphate; N7-Propargyl-7-deaza-2'-deoxyguanosine-5'-triphosphate trisodium salt
EINECS	Contact for details

Quality Control

Our 7-Ap-7-Deaza-Dgtp·3Na is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and in vitro diagnostic (IVD) applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or lyophilized powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or TE buffer
Biological Activity	Suitable for PCR/sequencing applications

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.