Description

Ac-Gly-Ala-Lys(Ac)-Amc is a specialized fluorogenic peptide substrate designed for high-sensitivity enzymatic assays. This compound is critical for researchers and quality control laboratories requiring precise measurement of protease activity. It is primarily utilized in the pharmaceutical, biotechnology, and diagnostic industries for drug discovery, biochemical research, and enzyme characterization.

Application

• Protease Activity Assays: As a fluorogenic substrate for the detection and quantification of specific protease enzymes in research and development.
• High-Throughput Screening (HTS): Used in drug discovery platforms to identify and characterize potential protease inhibitors.
• Biochemical Research: A key tool for studying enzyme kinetics, mechanism of action, and substrate specificity of proteolytic enzymes.
• Diagnostic Kit Development: Employed in the formulation of sensitive in-vitro diagnostic (IVD) tests for clinical analysis.
• Quality Control in Biologics: Monitoring protease activity during the production and purification of biopharmaceuticals to ensure product consistency and safety.

Basic Information

Product Name	Ac-Gly-Ala-Lys(Ac)-Amc
CAS No.	577969-56-3
Molecular Formula	C26H37N7O8
Molecular Weight	575.61 g/mol
Synonyms	Ac-Gly-Ala-Lys(Ac)-7-Amino-4-methylcoumarin; N-Acetyl-Glycyl-Alanyl-Nε-Acetyl-Lysyl-7-Amino-4-methylcoumarin; Ac-Gly-Ala-Lys(Ac)-AMC; Fluorogenic Protease Substrate Ac-Gly-Ala-Lys(Ac)-AMC; Ac-Gly-Ala-Lys(Ac)-AFC (common alternate); Ac-GAK(Ac)-AMC; Substrate for Plasmin and Related Proteases
EINECS	Contact for details

Quality Control

Every batch of Ac-Gly-Ala-Lys(Ac)-Amc is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure the highest standards of purity and performance. Our quality assurance protocol includes identity confirmation, purity assessment, and functional activity verification. Certificates of Analysis (COA) detailing lot-specific results are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Functional Activity	Conforms to reference standard
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.