Description

Decitabine is a potent and specific DNA methyltransferase inhibitor, playing a critical role in epigenetic regulation. This compound is essential for research and development in targeted cancer therapies, particularly for myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). It is a key raw material for pharmaceutical manufacturers, research institutions, and biotechnology companies focused on oncology and epigenetics.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of injectable oncology drugs.
• Critical reference standard and intermediate in pharmaceutical research and quality control laboratories.
• Core material for preclinical and clinical studies investigating hypomethylating agents.
• Essential component in the development of novel combination therapies for hematological cancers.
• Used in biochemical research to study DNA methylation patterns and epigenetic mechanisms.

Basic Information

Product Name	Decitabine
CAS No.	570410-70-7
Molecular Formula	C8H12N4O4
Molecular Weight	228.21 g/mol
Synonyms	5-Aza-2'-deoxycytidine; 5-Aza-dCyd; Dacogen (brand name); Dezocitidine; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one; NSC 127716; 2'-Deoxy-5-azacytidine
EINECS	Contact for details

Quality Control

Our Decitabine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) are provided, detailing specifications for identity, purity, and impurities, supporting compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) for long-term storage to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.