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Uridine 5'-(Trihydrogen Diphosphate) P'-(6-Azido-6-Deoxy-α-D-Glucopyranosyl) Ester CAS NO 537039-67-1
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CAS No.:537039-67-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Uridine 5'-(Trihydrogen Diphosphate) P'-(6-Azido-6-Deoxy-α-D-Glucopyranosyl) Ester is a specialized nucleotide sugar analog, a crucial biochemical building block for research and development. This compound matters for its role as a metabolic precursor and its utility in chemical biology, particularly in click chemistry applications due to its reactive azido functional group. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery, enzyme studies, and the synthesis of novel glycoconjugates.
Application
- Biochemical Research: Used as a substrate or intermediate in enzymatic studies, particularly those involving glycosyltransferases and nucleotide sugar metabolism.
- Pharmaceutical Development: Serves as a key precursor in the synthesis of novel nucleoside analogs and potential antiviral or anticancer agents.
- Chemical Biology & Click Chemistry: The 6-azido group enables efficient, bioorthogonal conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling biomolecules.
- Glycobiology Studies: Essential for investigating and manipulating glycosylation pathways and synthesizing defined oligosaccharide structures.
- Diagnostic Reagent Synthesis: Employed in the development of labeled probes and assay components for molecular diagnostics.
- Enzyme Inhibitor Design: Acts as a scaffold for designing inhibitors targeting specific enzymes in nucleotide sugar utilization pathways.
Basic Information
| Product Name | Uridine 5'-(Trihydrogen Diphosphate) P'-(6-Azido-6-Deoxy-α-D-Glucopyranosyl) Ester |
| CAS No. | 537039-67-1 |
| Molecular Formula | C15H22N5O16P2 |
| Molecular Weight | 590.31 g/mol |
| Synonyms | UDP-6-azido-6-deoxy-glucose; UDP-6-N3-Glc; 6-Azido-UDP-glucose; Uridine diphosphate 6-azido-6-deoxyglucose; UDP-α-D-6-azido-6-deoxyglucopyranose; 6-Azido-6-deoxy-UDP-glucose; Azido-UDP-Glc |
| EINECS | Contact for details |
Quality Control
Our Uridine 5'-(Trihydrogen Diphosphate) P'-(6-Azido-6-Deoxy-α-D-Glucopyranosyl) Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance processes.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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