Description

Androst-5-En-17-One, 16-Fluoro-3,7-Dihydroxy-, (3Alpha,7Beta,16Alpha)- (9Ci) is a high-purity fluorinated steroid derivative, a key intermediate in advanced pharmaceutical synthesis. Its precise stereochemistry and functional groups make it a critical building block for developing novel therapeutic agents with enhanced metabolic stability and receptor selectivity. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and biotechnology sectors, particularly those focused on endocrinology and metabolic disease treatments.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel steroid-based drugs and hormone therapies.
• Active Pharmaceutical Ingredient (API) Development: Used in R&D for creating new chemical entities targeting nuclear hormone receptors.
• Biochemical Research: Employed as a reference standard or probe in metabolic pathway studies and enzyme inhibition assays.
• Steroid Analog Synthesis: A key starting material for generating libraries of fluorinated steroid analogs for structure-activity relationship (SAR) studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	Androst-5-En-17-One, 16-Fluoro-3,7-Dihydroxy-, (3Alpha,7Beta,16Alpha)- (9Ci)
CAS No.	515159-76-9
Molecular Formula	C₁₉H₂₇FO₃
Molecular Weight	322.42 g/mol
Synonyms	16α-Fluoro-3α,7β-dihydroxyandrost-5-en-17-one; 16-Fluoro-3,7-dihydroxyandrost-5-en-17-one (3α,7β,16α-isomer); 16α-Fluoro-3α,7β-dihydroxy-5-androsten-17-one; (3α,7β,16α)-16-Fluoro-3,7-dihydroxyandrost-5-en-17-one; 515159-76-9; 16-Fluoro-3,7-dihydroxyandrost-5-en-17-one (9CI)
EINECS	Contact for details

Quality Control

Our Androst-5-En-17-One, 16-Fluoro-3,7-Dihydroxy-, (3Alpha,7Beta,16Alpha)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.